Symptoms of damage to parenchymal organs

Posted: May 16, 2012 in Pediatric surgery

The parenchyma are the functional parts of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, namely, the connective tissues.

In cancer, the parenchyma refers to the actual mutant cells of a single lineage, whereas the stroma is the surrounding connective tissue and associated cells that support it.

Liver :

The liver, the most vulnerable abdominal organ to blunt injury .Liver injuries present a serious risk for shock because the liver tissue is delicate and has a large blood supply and capacity. In children, the liver is the most commonly injured abdominal organ. The liver may be lacerated or contused, and a hematoma may develop. If severely injured, the liver may cause exsanguination (bleeding to death).


 Spleen is the most common damaged organ in blunt abdominal trauma. The spleen is the second most commonly injured intra-abdominal organ in children.  A laceration of the spleen may be associated with hematoma. The spleen, pancreas and kidneys do not present as much of an immediate threat of shock unless they lacerate a major blood vessel supplying the organs, such as the renal artery.

Pancreas :

 The pancreas may be injured in abdominal trauma, for example by laceration or contusion. Pancreatic injuries, most commonly caused by bicycle accidents (especially by impact with the handlebars) in children .

Kidneys :

The kidneys may also be injured; they are somewhat but not completely protected by the ribs. Kidney injury, a common finding in children with blunt abdominal trauma, may be associated with bloody urine. Kidney lacerations and contusions may also occur.

Organ Parenchyma
Brain Neurons & Glial Cells
Heart Myocytes
Kidney Nephrons
Liver Hepatocytes
Lungs Alveolar Tissue
Pancreas Islets of Langerhans & Pancreatic Acini
Spleen White & Red Pulps
Placenta placental villi, including the fetal vessels, and the maternal intervillous space

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